Publications 2024

Direct delivery of Cas9 or base editor protein and guide RNA complex enables genome editing in the retina. Pulman J, Botto C, Malki H, Ren D, Oudin P, De Cian A, As M, Izabelle C, Saubamea B, Forster V, Fouquet S, Robert C, Portal C, El-Amraoui A, Fisson S, Concordet JP, Dalkara D. Mol Ther Nucleic Acids. 2024 Sep 30;35(4):102349. doi: 10.1016/j.omtn.2024.102349.

Harlequin mice exhibit cognitive impairment, severe loss of Purkinje cells and a compromised bioenergetic status due to the absence of Apoptosis Inducing Factor. Cwerman-Thibault H, Malko-Baverel V, Le Guilloux G, Torres-Cuevas I, Ratcliffe E, Mouri D, Mignon V, Saubaméa B, Boespflug-Tanguy O, Gressens P, Corral-Debrinski M. Biochim Biophys Acta Mol Basis Dis. 2024 Oct;1870(7):167272. doi: 10.1016/j.bbadis.2024.167272. Epub 2024 Jun 17. PMID: 38897257

Neuroglobin overexpression in cerebellar neurons of Harlequin mice improves mitochondrial homeostasis and reduces ataxic behavior. Cwerman-Thibault H, Malko-Baverel V, Le Guilloux G, Ratcliffe E, Mouri D, Torres-Cuevas I, Millán I, Saubaméa B, Mignon V, Boespflug-Tanguy O, Gressens P, Corral-Debrinski M. Molecular Therapy. 2024 Jul 3;32(7):2150-2175. doi: 10.1016/j.ymthe.2024.05.030. Epub 2024 May 24. PMID: 38796706

Exposure to PM2.5 modulate the pro-inflammatory and interferon responses against influenza virus infection in a human 3D bronchial epithelium model. Chivé C, Martίn-Faivre L, Eon-Bertho A, Alwardini C, Degrouard J, Albinet A, Noyalet G, Chevaillier S, Maisonneuve F, Sallenave JM, Devineau S, Michoud V, Garcia-Verdugo I, Baeza-Squiban A. Environ Pollut. 2024 Mar 14;348:123781. doi: 10.1016/j.envpol.2024.123781.

Specific interaction between Group B Streptococcus CC17 hypervirulent clone and phagocytes. Bourrel A-S, Picart A, Fernandez J-C, Hays C, Mignon V, Saubaméa B, Poyart C, Fouet A, Tazi A, Guignot J. Infect Immun. 2024 Mar 22:e0006224. doi: 10.1128/iai.00062-24.

Intracellular Delivery of Functional Proteins with DNA-Protein Nanogels-Lipids Complex. Marina Mariconti, Laurie Dechamboux, Marion Heckmann, Julien Gros, Mathieu Morel, Virginie Escriou, Damien Baigl, Céline Hoffmann, Sergii Rudiuk. J Am Chem Soc. 2024 Feb 28;146(8):5118-5127. doi: 10.1021/jacs.3c08000. Epub 2024 Feb 16.

Hemocompatibility and biophysical interface of left ventricular assist devices and total artificial hearts. Nascimbene A, Bark D, Smadja DM. Blood. 2024 Feb 22;143(8):661-672. doi: 10.1182/blood.2022018096.

Co-encapsulation of fisetin and cisplatin into liposomes: Stability considerations and in vivo efficacy on lung cancer animal model. Renault-Mahieux M, Seguin J, Vieillard V, Le DT, Espeau P, Lai-Kuen R, Richard C, Mignet N, Paul M, Andrieux K. Int J Pharm. 2024 Feb 15;651:123744. doi: 10.1016/j.ijpharm.2023.123744.

Step-By-Step Standardization of the Bottom-Up Semi-Automated Nanocrystallization of Pharmaceuticals: A Quality By Design and Design of Experiments Joint Approach. Castillo Henríquez L, Bahloul B, Alhareth K, Oyoun F, Frejková M, Kostka L, Etrych T, Kalshoven L, Guillaume A, Mignet N, Corvis Y. Small. 2024 Feb 1:e2306054. doi: 10.1002/smll.202306054. PMID: 38299478

Dynamic local mRNA distribution and translation influence the postnatal molecular maturation of perivascular astrocytic processes. Katia Avila-Gutierrez, Leila Slaoui, Rodrigo Alvear, Esther Kozlowski, Marc Florian Oudart, Emma Augustin, Philippe Mailly, Heloise Monnet, Virginie Mignon, Bruno Saubamea, Anne-Cecile Boulay, and Martine Cohen-Salmon. Glia. 2024 Jan 8. doi: 10.1002/glia.24503. Online ahead of print.